abNEX™ Targeted NGS

From sample to pathogen or tumor report, all on one platform.

abNEX™ converts total nucleic acid into target-enriched, dual-barcoded libraries. These are read on the compact, lightweight abSEQ™ sequencer and analysed onboard. One integrated workflow across infectious disease and oncology.

Request a Demo

476

Pathogens detected

Resistance genes

Clinical panels

copies/mL LoD

The workflow

One sample-to-report pipeline

Every abNEX™ panel runs the same four-stage path: extraction, library preparation, sequencing, and analysis. A lab can move from specimen to structured report without leaving the platform.

abGenix™

EXTRACTION

Automated DNA & RNA co-extraction from the primary specimen.

abNEX™

LIBRARY PREP

Target enrichment and unique dual-barcode library construction.

abSEQ™

SEQUENCING

Compact, lightweight DNA-nanoball sequencing; up to 48 barcoded samples per run.

abTRON™

ANALYSIS

On-premise pathogen, resistance & virulence reporting.

Note: abTRON™ analysis covers the infectious-disease panels (Pan-Infection & MTB). The oncology panel is analysed through its own validated bioinformatics pipeline and can also be sequenced on Illumina® platforms.

Flexible enrichment

Two chemistries, unlimited library possibilities

abNEX™ matches the enrichment chemistry to the application: high-sensitivity amplification for pathogens, and probe-based capture for comprehensive tumor profiling.

Amplicon · HyPA

Hyperplex Precise Amplification

Multiplex-PCR amplicon enrichment delivers high sensitivity from low-input, host-rich specimens with a simple, fast workflow, ideal for detecting low-abundance and co-infecting organisms.

Used for: Pan-Infection & MTB

Hybridization capture

Probe-based target capture

Biotinylated probes hybridize and magnetically enrich 188 somatic targets, capturing SNVs, InDels, CNVs, gene fusions and MSI across challenging sample types including FFPE and cfDNA.

Used for: Oncology (Onco 188)

Applications

Choose your panel

Each abNEX™ panel pairs a validated target set with the right enrichment chemistry for its application.

Amplicon enrichment · HyPA

abNEX™ Pan-Infection

Broad-range pathogen, resistance and virulence profiling in a single targeted-NGS reaction, with semi-quantitative load in copies/mL. An upfront reverse-transcription step captures RNA pathogens.

476

Pathogens detected

Drug-resistance genes

Virulence genes

Reportable range120 bacteria, 76 MTB/NTM, 101 RNA viruses, 70 DNA viruses, 66 fungi, 27 parasites, 16 atypicals (Mycoplasma, Chlamydia, Rickettsia)

Specimen typesSputum, BALF, CSF, nasopharyngeal swab, pleural fluid, and other infected fluids

Sensitivity (LoD)50 copies/mL

AnalysisabTRON™ Intelligent Center

Library workflowExtract→RT (RNA)→Enrich PCR1→UDB barcode PCR2→Pool ≤48→abSEQ™→abTRON™

For Assay Partners

Have a tNGS panel? Run it on abSEQ™.

abSEQ™ is panel-agnostic, and abNEX™ libraries already run on both abSEQ™ and Illumina® systems. If you develop qPCR/MDx or targeted-NGS assays without an instrument of your own, partner with AITbiotech to deploy your validated panel on our open platform.

Become a Partner →